Article
Radially patterned cell behaviours during tube budding from an epithelium.
eLife - 17 Jul 2018
Sanchez-Corrales Yara E, Blanchard Guy B, Röper Katja
Abstract excerpt
The budding of tubular organs from flat epithelial sheets is a vital morphogenetic process. Cell behaviours that drive such processes are only starting to be unraveled. Using live-imaging and novel morphometric methods, we show that in addition to apical constriction, radially oriented directional intercalation of cells plays a major contribution to early stages of invagination of the salivary gland tube in the...
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