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Article

CHCHD10 variants in amyotrophic lateral sclerosis: Where is the evidence?

Annals of neurology - 1 Jul 2018

Abstract excerpt

OBJECTIVE: After the initial report of a CHCHD10 mutation in mitochondrial disease with features resembling amyotrophic lateral sclerosis (ALS), CHCHD10 mutations have been considered to be a frequent cause for ALS. However, the exact pathogenicity and clinical significance of these mutations remain unclear. Here, we aimed to determine the role of CHCHD10 mutations in ALS. METHODS: We analyzed 4,365 whole genome...

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Identifiers

PMID: 30014597
DOI: 10.1002/ana.25273
PMCID: PMC6553489

Genes

CHCHD10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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