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Article

COL18A1 is a candidate eye iridocorneal angle-closure gene in humans.

Human molecular genetics - 1 Nov 2018

Suri Fatemeh, Yazdani Shahin, Chapi Marjan, Safari Iman, Rasooli Paniz, Daftarian Narsis, Jafarinasab Mohammad Reza, Ghasemi Firouzabadi Saghar, Alehabib Elham, Darvish Hossein, Klotzle Brandy, Fan Jian-Bing, Turk Casey, Elahi Elahe

Abstract excerpt

Primary angle-closure glaucoma (PACG) is a common form of glaucoma in the Far East. Its defining feature is iridocorneal angle closure. In addition to PACG, indications of angle closure are included in the diagnostic criteria of related conditions primary angle-closure suspect (PACS) and primary angle closure (PAC). To the best of our knowledge, a causative gene for iridocorneal angle closure in humans has not...

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PMID: 30007336
DOI: 10.1093/hmg/ddy256

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