Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Response to Checkpoint Inhibitor Therapy in Advanced Classic Kaposi Sarcoma: A Case Report and Immunogenomic Study.

Journal of the National Comprehensive Cancer Network : JNCCN - 1 Jul 2018

Saller James, Walko Christine M, Millis Sherri Z, Henderson-Jackson Evita, Makanji Rikesh, Brohl Andrew S

Abstract excerpt

Kaposi sarcoma (KS) is an uncommon angioproliferative malignancy that is associated with human herpesvirus 8. Although there has been recent enthusiasm for evaluating immune checkpoint inhibition as a therapeutic option for viral-associated tumors, the clinical utility in this disease is currently unknown. We report a case of advanced classic KS refractory to multiple lines of chemotherapy that experienced a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents, Immunological
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biopsy

Share to Drug Resistance, Neoplasm

Share to Herpesvirus 8, Human

Share to Programmed Cell Death 1 Receptor

Share to Sarcoma, Kaposi

Share to Treatment Outcome

Source

Identifiers

PMID: 30006421
DOI: 10.6004/jnccn.2018.7018

Genes

KRAS
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Response to Checkpoint Inhibitor Therapy in Advanced Classic Kaposi Sarcoma: A Case Report and Immunogenomic Study.PMID 30006421Read ↗

Classic Kaposi sarcoma: Diagnostics, treatment modalities, and genetic implications - A review of the literature.Semantic proximity Read ↗

Genetic landscape of indolent and aggressive Kaposi sarcomas.Semantic proximity Read ↗

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapySemantic proximity Read ↗

Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesisSemantic proximity Read ↗

Integrative Functional Genomics Analysis of Kaposi Sarcoma CohortsSemantic proximity Read ↗

Transcriptional analysis identifies overlapping and tissue-distinct profiles between Kaposi sarcoma tumors of the skin and gastrointestinal tractSemantic proximity Read ↗

Spatial and Bulk Transcriptomics Reveal Distinct Molecular Signatures in Kaposi Sarcoma with and Without other KSHV-Associated DiseasesSemantic proximity Read ↗

Integrative functional genomics analysis of Kaposi sarcoma cohortsSemantic proximity Read ↗

Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment decision in end-stage disease.Semantic proximity Read ↗

INTEGRATIVE FUNCTIONAL GENOMICS ANALYSIS OF KAPOSI'S SARCOMA COHORTSSemantic proximity Read ↗

Molecular Genetics of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Epidemiology and PathogenesisSemantic proximity Read ↗

Molecular Mechanisms of Kaposi Sarcoma DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.