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Article

Sucrose Nonfermenting 1-Related Protein Kinase 1 Phosphorylates a Geminivirus Rep Protein to Impair Viral Replication and Infection.

Plant physiology - 1 Sept 2018

Shen Wei, Bobay Benjamin G, Greeley Laura A, Reyes Maria I, Rajabu Cyprian A, Blackburn R Kevin, Dallas Mary Beth, Goshe Michael B, Ascencio-Ibáñez Jose T, Hanley-Bowdoin Linda

Abstract excerpt

Geminiviruses are single-stranded DNA viruses that infect a wide variety of plants and cause severe crop losses worldwide. The geminivirus replication initiator protein (Rep) binds to the viral replication origin and catalyzes DNA cleavage and ligation to initiate rolling circle replication. In this study, we found that the Tomato golden mosaic virus (TGMV) Rep is phosphorylated at serine-97 by sucrose...

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Identifiers

PMID: 30006378
DOI: 10.1104/pp.18.00268
PMCID: PMC6130039

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