Ethnic variation in the incidence of biliary atresia correlates with the frequency of the most prevalent haplotype in its population.

doi:10.1016/j.humimm.2018.07.001

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Ethnic variation in the incidence of biliary atresia correlates with the frequency of the most prevalent haplotype in its population.

Human immunology - 1 Sept 2018

Muraji Toshihiro, Tanaka Hidenori, Ieiri Satoshi

Abstract excerpt

The cause of biliary atresia (BA) remains an enigma. However, an ethnic diversity in the incidence of BA is so unique that anthropological approach may provide some etiopathogenetic implications in the disease mechanism. We previously reported that an association of maternal microchimerism (MMc) in BA and a significant compatibility of HLA-A between the patient with BA and their mother. Across the 10 countries...

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Ethnic variation in the incidence of biliary atresia correlates with the frequency of the most prevalent haplotype in its population.

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