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TNF-alpha G/A308 polymorphism association with nasal polyposis in North part of Iran.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Sept 2018

Faghani Masoumeh, Keshavars Parvaneh, Sharafshah Alireza, Pourgholamali Babak, Moharami Farshad, Nemati Shadman

Abstract excerpt

Nasal Polyposis (NP) is a complex multi-factorial disease; associated with several environmental, genetic and inflammatory factors. TNF-alpha is one of the major pro-inflammatory cytokines involved in NP pathogenesis. Some of the polymorphisms of this gene affect its expression. Therefore, the aim of this study was to evaluate the polymorphism of TNF-alpha G/A308 gene and its association with nasal polyposis in...

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PMID: 30003390
DOI: 10.1007/s00405-018-5059-4

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TNF

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