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Article

Role of Activator Protein-1 Complex on the Phenotype of Human Osteosarcomas Generated from Mesenchymal Stem Cells.

Stem cells (Dayton, Ohio) - 1 Oct 2018

Gambera Stefano, Abarrategi Ander, Rodríguez-Milla Miguel A, Mulero Francisca, Menéndez Sofía T, Rodriguez René, Navarro Samuel, García-Castro Javier

Abstract excerpt

Osteosarcoma (OS) is a highly aggressive bone tumor that usually arises intramedullary at the extremities of long bones. Due to the fact that the peak of incidence is in the growth spurt of adolescence, the specific anatomical location, and the heterogeneity of cells, it is believed that osteosarcomagenesis is a process associated with bone development. Different studies in murine models showed that the...

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Source

Identifiers

PMID: 30001480
DOI: 10.1002/stem.2869

Genes

JUN
FOS
MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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