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Article

[Feasibility of amplicon-based targeted next-generation sequencing of colorectal cancer in endoscopic biopsies].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Jul 2018

Wang Y J, Jiang R R, Liu H J, Zhang B, Ye F, Bu H

Abstract excerpt

Objective: To investigate whether small endoscopic biopsies of colorectal cancer were sufficient for quality and accurate mutational analysis by amplicon-based next-generation sequencing (NGS). Methods: By using an amplicon-based targeted NGS panel for mutational detection on Illumina Miseq platform, a total of 109 formalin-fixed and paraffin-embedded (FFPE) endoscopic biopsies of colorectal cancer were...

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Identifiers

PMID: 29996313
DOI: 10.3760/cma.j.issn.0529-5807.2018.07.004

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BRAF
KRAS

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