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Article

Cladribine: mechanisms and mysteries in multiple sclerosis

10 Jul 2018

Abstract excerpt

OBJECTIVES: The aims of this manuscript were to review the evidence for the efficacy and safety of cladribine in multiple sclerosis (MS) and to review the molecular and cellular mechanisms by which cladribine acts as a disease-modifying therapy in MS. METHODS: This is a narrative review of the available clinical and preclinical data on the use of cladribine in MS. RESULTS: Clinical trial data argue strongly that...

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PMID: 29991490
DOI: 10.1136/jnnp-2017-317411

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