Article
Anti-neutral glycolipids antibody-positive combined central and peripheral demyelination mimicking encephalomyeloradiculoneuropathy phenotype.
Clinical neurology and neurosurgery - 1 Sept 2018
Saito Kazuyuki, Toru Shuta, Shima Sayuri, Mutoh Tatsuro
Abstract excerpt
We herein report the first combined central and peripheral demyelination (CCPD) case originally diagnosed as multifocal acquired demyelinating sensory and motor neuropathy followed by CNS impairments with a long lag time (160 days after first attack). The anti-neutral glycolipids antibodies, especially anti-lactosylceramide antibodies but not anti-NF155 antibodies typical for CCPD were detected in the acute phase...
Topics
- Autoantibodies
- Cerebrospinal Fluid
- Glycolipids
- Humans
- Male
- Middle Aged
- Nervous System Malformations
- Phenotype
- Polyradiculoneuropathy, Chronic Inflammatory Demyelinating