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Antiganglioside antibodies and their pathophysiological effects on Guillain-Barre syndrome and related disorders--A review

24 Feb 2009

Abstract excerpt

Guillain-Barré syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy which can cause acute quadriplegia. Infection with micro-organisms, including Campylobacter jejuni (C. jejuni), Haemophilus influenzae, and Cytomegalovirus (CMV), is recognized as a main triggering event for the disease. Lipooligosaccharide (LOS) genes are responsible for the formation of human ganglioside-like LOS structures in...

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PMID: 19240270
DOI: 10.1093/glycob/cwp027

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