Article
Progressive Leukodystrophy-Like Demyelinating Syndromes with MOG-Antibodies in Children: A Rare Under-Recognized Phenotype.
Neuropediatrics - 1 Aug 2021
Yazbeck Elise, Maurey Hélène, Leroy Carole, Horellou Philippe, Napuri Silvia, Lali Mohammed, Adam Clovis, Husson Beatrice, Sevin Caroline, Deiva Kumaran
Abstract excerpt
Acquired demyelinating syndromes (ADS) are frequently associated with myelin oligodendrocytes glycoprotein (MOG) antibodies in children. Clinical phenotypes are heterogeneous and may delay the diagnosis, especially when they relapse and are atypical, mimicking diseases such as multiple sclerosis or neuromyelitis optica spectrum disorders . Here, we describe two children: one with a progressive cognitive and...
Topics
- Autoantibodies
- Humans
- Myelin-Oligodendrocyte Glycoprotein
- Neuromyelitis Optica
- Phenotype
- Retrospective Studies
- Syndrome
