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Article

Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations.

Microbial genomics - 1 Sept 2018

Lam Margaret M C, Wick Ryan R, Wyres Kelly L, Gorrie Claire L, Judd Louise M, Jenney Adam W J, Brisse Sylvain, Holt Kathryn E

Abstract excerpt

Mobile genetic elements (MGEs) that frequently transfer within and between bacterial species play a critical role in bacterial evolution, and often carry key accessory genes that associate with a bacteria's ability to cause disease. MGEs carrying antimicrobial resistance (AMR) and/or virulence determinants are common in the opportunistic pathogen Klebsiella pneumoniae, which is a leading cause of highly...

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PMID: 29985125
DOI: 10.1099/mgen.0.000196
PMCID: PMC6202445

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