Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms.

doi:10.1186/1471-2164-15-54

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Article

Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms.

BMC genomics - 22 Jan 2014

Ramos Pablo Ivan Pereira, Picão Renata Christina, Almeida Luiz Gonzaga Paula de, Lima Nicholas Costa B, Girardello Raquel, Vivan Ana Carolina P, Xavier Danilo E, Barcellos Fernando G, Pelisson Marsileni, Vespero Eliana C, Médigue Claudine, Vasconcelos Ana Tereza Ribeiro de, Gales Ana Cristina, Nicolás Marisa Fabiana

Abstract excerpt

BACKGROUND: Klebsiella pneumoniae is an important opportunistic pathogen associated with nosocomial and community-acquired infections. A wide repertoire of virulence and antimicrobial resistance genes is present in K. pneumoniae genomes, which can constitute extra challenges in the treatment of infections caused by some strains. K. pneumoniae Kp13 is a multidrug-resistant strain responsible for causing a large...

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PMID: 24450656
DOI: 10.1186/1471-2164-15-54
PMCID: PMC3904158

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