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Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells

3 Jul 2018

Abstract excerpt

Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus. Here, we examined entry of CRCoV into human rectal tumor cells (HRT-18G cell line) by analyzing co-localization of single virus particles with cellular markers in the presence or absence of chemical inhibitors of...

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PMID: 29970183
DOI: 10.1186/s13567-018-0551-9

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