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Article

Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2018

Song Wenzhe, Thakor Parth, Vesey David A, Gobe Glenda C, Morais Christudas

Abstract excerpt

Disparate roles exist for tumor-associated macrophages in breast cancer growth and progression. The aim of this study was to explore the influence of induced macrophages on the growth of breast cancer cells. THP-1 monocytes were differentiated to macrophages using phorbol 12-myristate 13-acetate. The effect of the medium from THP-1 monocytes or macrophage-conditioned medium (MφCM) on MCF-7 (estrogen receptor and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29966967
DOI: 10.1016/j.biopha.2018.06.126

Genes

GLB1
PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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