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Article

Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.

PloS one - 1 Jan 2018

Wittkowski Knut M, Dadurian Christina, Seybold Martin P, Kim Han Sang, Hoshino Ayuko, Lyden David

Abstract excerpt

Most breast cancer deaths are caused by metastasis and treatment options beyond radiation and cytotoxic drugs, which have severe side effects, and hormonal treatments, which are or become ineffective for many patients, are urgently needed. This study reanalyzed existing data from three genome-wide association studies (GWAS) using a novel computational biostatistics approach (muGWAS), which had been validated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29965997
DOI: 10.1371/journal.pone.0199012
PMCID: PMC6028090

Genes

ABCA1
AGPAT3
AGPAT4
ANO4
DGKQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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