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Article

Knockdown of FUT3 disrupts the proliferation, migration, tumorigenesis and TGF‑β induced EMT in pancreatic cancer cells

18 May 2018

Abstract excerpt

Fucosyltransferases (FUTs) are critical for glycoproteins and glycolipid chains and serve an important role in the adhesive interaction between selectins and their ligands, which contribute to tumor cell spread and metastasis. While multiple cancer cell lines heavily express FUT3, the present study investigated the expression level of FUT3 in different human pancreatic cancer cell lines. Forced expression and...

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Identifiers

PMID: 29963165
DOI: 10.3892/ol.2018.8738

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