Article
Metabolic reprogramming-based characterization of circulating tumor cells in prostate cancer.
Journal of experimental & clinical cancer research : CR - 28 Jun 2018
Chen Jing, Cao Shunwang, Situ Bo, Zhong Juan, Hu Yanwei, Li Shufen, Huang Jinlan, Xu Jiasen, Wu Shiyang, Lin Jinduan, Zhao Qianwen, Cai Zhen, Zheng Lei, Wang Qian
Abstract excerpt
BACKGROUND: Circulating tumor cells (CTCs), an advantageous target of liquid biopsy, is an important biomarker for the prognosis and monitoring of cancer. Currently, detection techniques for CTCs are mainly based on the physical and/or epithelial characteristics of tumor cells. However, biofunctional activity markers that can indicate the high metastatic capacity of CTCs are lacking. METHODS: Functional...
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