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Inhibition of Pseudomonas aeruginosa secreted virulence factors reduces lung inflammation in CF mice

25 Jun 2018

Abstract excerpt

BACKGROUND: Cystic fibrosis (CF) lung infection is a complex condition where opportunistic pathogens and defective immune system cooperate in developing a constant cycle of infection and inflammation. The major pathogen, Pseudomonas aeruginosa, secretes a multitude of virulence factors involved in host immune response and lung tissue damage. In this study, we examined the possible anti-inflammatory effects of...

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PMID: 29938577
DOI: 10.1080/21505594.2018.1489198

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