Article
Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy.
BMC gastroenterology - 22 Jun 2018
Taylor Ripley R, Surman Deborah R, Diggs Laurence P, Trepel Jane B, Lee Min-Jung, Ryan Jeremy, Davis Jeremy L, Steinberg Seth M, Hernandez Jonathan M, Hoang Choung, Kenney Cara M, Bond Colleen D, Kunst Tricia F, Letai Anthony, Schrump David S
Abstract excerpt
BACKGROUND: Esophageal cancers accounted for nearly 16,000 deaths in 2016. The number of patients with esophageal cancers increases every year. Neoadjuvant chemoradiotherapy (nCRT) prior to esophagectomy is a standard treatment for esophageal cancers. The patients who have no residual tumor (pathological complete response (pCR)) at surgery are the most likely to experience long term survival. Accurately...
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