Article
Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta).
Scientific reports - 20 Jun 2018
Fukuda Tomokazu, Eitsuka Takahiro, Donai Kenichiro, Kurita Masanori, Saito Tomomi, Okamoto Hitoshi, Kinoshita Kodzue, Katayama Masafumi, Nitto Hiroshi, Uchida Takafumi, Onuma Manabu, Sone Hideko, Inoue-Murayama Miho, Kiyono Tohru
Abstract excerpt
Conservation of the genetic resources of endangered animals is crucial for future generations. The loggerhead sea turtle (Caretta caretta) is a critically endangered species, because of human hunting, hybridisation with other sea turtle species, and infectious diseases. In the present study, we established primary fibroblast cell lines from the loggerhead sea turtle, and showed its species specific chromosome...
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