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Article

Genomic insights into the causes of type 2 diabetes.

Lancet (London, England) - 16 Jun 2018

Langenberg Claudia, Lotta Luca A

Abstract excerpt

Genome-wide association studies have implicated around 250 genomic regions in predisposition to type 2 diabetes, with evidence for causal variants and genes emerging for several of these regions. Understanding of the underlying mechanisms, including the interplay between β-cell failure, insulin sensitivity, appetite regulation, and adipose storage has been facilitated by the integration of multidimensional data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29916387
DOI: 10.1016/S0140-6736(18)31132-2

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