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Article

Gene expression analysis of nidus of cerebral arteriovenous malformations reveals vascular structures with deficient differentiation and maturation

13 Jun 2018

Abstract excerpt

OBJECTIVE: Arteriovenous malformations (AVMs) are characterised by tangles of dysplastic blood vessels which shunt blood from arteries to veins with no intervening capillary bed. It is not known at what stage of development and differentiation, AVM vessels became aberrant. To address this, we have analysed the expression of vascular differentiation, vascular maturation and brain capillary specific genes in AVM...

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Share to Intracerebral and Subarachnoid Hemorrhage Research
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PMID: 29897969
DOI: 10.1371/journal.pone.0198617

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