Article
Development of a Japanese encephalitis virus genotype V virus-like particle vaccine in silkworms.
The Journal of general virology - 1 Jul 2018
Nerome Kuniaki, Yamaguchi Ryoji, Fuke Naoyuki, Izzati Uda Zahli, Maegawa Kenichi, Sugita Shigeo, Kawasaki Kazunori, Kuroda Kazumichi, Nerome Reiko
Abstract excerpt
To counter the spread of multiple Japanese encephalitis virus (JEV) variants harboured in alternative host species and highly neurotoxic variants with new antigenicity, such as genotype V (Muar), methods for developing more effective and low-cost vaccines against a variety of epidemic JEV strains are required. Here, we successfully synthesized large amounts of a Muar virus-like particle (MVLP) vaccine for JEV in...
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