Article
Detection of BRAF V600E Mutations With Next-Generation Sequencing in Infarcted Thyroid Carcinomas After Fine-Needle Aspiration.
American journal of clinical pathology - 3 Jul 2018
Kouba Erik, Ford Andrew, Brown Charmaine G, Yeh Chen, Siegal Gene P, Manne Upender, Eltoum Isam-Eldin
Abstract excerpt
OBJECTIVES: Fine-needle aspiration (FNA) of thyroid lesions may result in infarction and diagnostic difficulties on subsequent thyroidectomy specimens. Next-generation sequencing (NGS) methods for detection of hallmark driver BRAF V600E mutations may help characterize such tumors in which histologic alterations preclude definitive tissue diagnosis. METHODS: Thyroidectomy specimens with both malignant FNA...
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