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Article

Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells

15 May 2018

Abstract excerpt

Purpose: Corneal endothelial cells (CECs) are critical in maintaining clarity of the cornea. This study was initiated to develop peripheral blood mononuclear cell (PBMC)-originated, induced pluripotent stem cell (iPSC)-derived CECs. Methods: We isolated PBMCs and programmed the mononuclear cells to generate iPSCs, which were differentiated to CECs through the neural crest cells (NCCs). The morphology of...

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PMID: 29847650
DOI: 10.1167/iovs.17-22927

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