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The Association between E326K of GBA and the Risk of Parkinson’s Disease

1 Jan 2018

Abstract excerpt

It is reported that both the homozygous and heterozygous states of GBA mutations which are the causes of Gaucher disease (GD) are linked to the risk of PD. However, the GBA variant p.E326K (c.1093G > A, rs2230288), which does not result in GD in homozygous carriers, has triggered debate among experts studying Parkinson's disease (PD). In order to determine if the E326K variant of GBA is associated with the risk...

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PMID: 29808112
DOI: 10.1155/2018/1048084

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