A common polymorphism in the SCN5A gene is associated with dilated cardiomyopathy.

doi:10.2459/JCM.0000000000000670

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Article

A common polymorphism in the SCN5A gene is associated with dilated cardiomyopathy.

Journal of cardiovascular medicine (Hagerstown, Md.) - 1 Jul 2018

Mazzaccara Cristina, Limongelli Giuseppe, Petretta Mario, Vastarella Rossella, Pacileo Giuseppe, Bonaduce Domenico, Salvatore Francesco, Frisso Giulia

Abstract excerpt

AIMS: SCN5A is a disease-causing gene associated with familial dilated cardiomyopathy (FDC). We examined the possible association between a common polymorphism in the SCN5A gene (c.1673A>G-p.H558R; rs1805124) and the risk of dilated cardiomyopathy (DCM) occurrence. METHODS: We genotyped 185 DCM cases (familial DCM, idiopathic DCM and postischemic DCM) and 251 controls for the p.H558R polymorphism in the SCN5A...

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PMID: 29782370
DOI: 10.2459/JCM.0000000000000670
PMCID: PMC6012048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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