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[Association of polymorphism 4a/4b and 4b/4b in endothelial nitric oxide synthase gene and markers of endothelial dysfunction in patients with chronic heart failure].

Kardiologiia - 1 Jan 2000

Polunina E A, Voronina L P, Sevostyanova I V, Polunina O S, Tarasochkina D S

Abstract excerpt

AIM: To examine the association of polymorphism 4a/4b and 4b/4b in endothelial nitric oxide synthase gene (eNOS) with levels of natriuretic peptide type-C, endothelin-1 and vasoregulative endothelial function in patients with chronic heart failure (CHF) depending on the ejection fraction of the left ventricle. MATERIALS AND METHODS: The study has included 280 patients with CHF of ischemic etiology and 60...

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PMID: 29782277

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