Article
Microarray analysis of circular RNA expression profiles associated with gemcitabine resistance in pancreatic cancer cells
17 May 2018
Abstract excerpt
Pancreatic cancer (PC) is one of the most malignant tumors of the digestive system due to its rapid progression, metastasis and resistance to chemotherapy. Gemcitabine (GEM) chemotherapy is the first‑choice treatment for advanced PC. However, the effect of GEM‑based chemotherapy on PC is limited due to the development of chemoresistance, and the molecular mechanisms underlying this resistance have yet to be...
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