Article
Reverse line probe assay for cheap detection of Single Nucleotide Polymorphisms in Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) - 1 May 2018
Yasmin Memona, Refregier Guislaine, Siddiqui Rubina Tabassum, Iqbal Rizwan, Abbasi Shahid Ahmad, Tahseen Sabira
Abstract excerpt
More and more Single Nucleotide Polymosrphisms of interest among pathogenic organisms are described with the advent of Whole Genome Sequencing but WGS approach is still too expensive, time consuming, and relying on bioinformatical means that are not available in many developing countries. This study presents a low-cost reverse hybridization line probe technique for detecting SNPs in Mycobacterium tuberculosis....
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