Autosomal-dominant cerebellar ataxias.

Abstract excerpt

Spinocerebellar ataxias (SCAs) are a genetically diverse group of dominantly inherited disorders that share clinical features that result from dysfunction and degeneration of the cerebellum and its associated pathways. Although nearly 40 genes are currently recognized to result in SCA, shared mechanisms for disease pathogenesis exist among subsets of the SCAs. The most common SCAs result from a glutamine-encoding...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cerebellum
• Share to Genes, Dominant
• Share to Genetic Variation