Article
Dietary mung bean protein reduces high-fat diet-induced weight gain by modulating host bile acid metabolism in a gut microbiota-dependent manner.
Biochemical and biophysical research communications - 2 Jul 2018
Nakatani Akiho, Li Xuan, Miyamoto Junki, Igarashi Miki, Watanabe Hitoshi, Sutou Asuka, Watanabe Keita, Motoyama Takayasu, Tachibana Nobuhiko, Kohno Mitsutaka, Inoue Hiroshi, Kimura Ikuo
Abstract excerpt
The 8-globulin-rich mung bean protein (MPI) suppresses hepatic lipogenesis in rodent models and reduces fasting plasma glucose and insulin levels in obese adults. However, its effects on mitigating high fat diet (HFD)-induced obesity and the mechanism underlying these effects remain to be elucidated. Herein, we examined the metabolic phenotype, intestinal bile acid (BA) pool, and gut microbiota of conventionally...
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