Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucocorticoid signaling regulates cell invasion and migration in the human first‐trimester trophoblast cell line Sw.71

18 May 2018

Abstract excerpt

PROBLEM: The development of the placenta and its functions are sensitive to infection and stress, which can activate the hypothalamic-pituitary-adrenal axis. Adrenally produced glucocorticoids are the body's primary mediators of the inflammatory and stress response. Although the glucocorticoid receptor (GR) is expressed in all human villous trophoblast tissue, the effect of glucocorticoids on placentation is not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pregnancy and preeclampsia studies
Share to Preterm Birth and Chorioamnionitis
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29774963
DOI: 10.1111/aji.12974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucocorticoid signaling regulates cell invasion and migration in the human first‐trimester trophoblast cell line Sw.71PMID 29774963Read ↗

Global Gene Expression Analysis in Human Uterine Epithelial Cells Defines New Targets of Glucocorticoid and Estradiol Antagonism1Semantic proximity Read ↗

Reduced cell invasion may be a characteristic of placental defects in pregnant women of advanced maternal age at single-cell levelSemantic proximity Read ↗

Let-7b-5p differentially regulates human first trimester trophoblast migration and sFlt-1 through TLR7 and TLR8Semantic proximity Read ↗

Prenatal exposure to dexamethasone in the mouse induces sex‐specific differences in placental gene expressionSemantic proximity Read ↗

Metabolism of cholesterol and progesterone is differentially regulated in primary trophoblastic subtypes and might be disturbed in recurrent miscarriagesSemantic proximity Read ↗

Glucocorticoids Regulate Gene Expression and Repress Cellular Proliferation in Human Uterine Leiomyoma CellsSemantic proximity Read ↗

Function and Hormonal Regulation of GATA3 in Human First Trimester PlacentationSemantic proximity Read ↗

The human placenta expresses multiple glucocorticoid receptor isoforms that are altered by fetal sex, growth restriction and maternal asthmaSemantic proximity Read ↗

Glucocorticoid Receptor Regulated KCNA5 Mediates Cell Proliferation in Human Fetal MembranesSemantic proximity Read ↗

Estradiol promotes trophoblast viability and invasion by activating SGK1Semantic proximity Read ↗

Nuclear receptor coactivator 6 promotes HTR‐8/SVneo cell invasion and migration by activating NF‐κB‐mediated MMP9 transcriptionSemantic proximity Read ↗

RelB/NF-κB2 Regulates Corticotropin-Releasing Hormone in the Human PlacentaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.