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Article

Tumor Necrosis Factor: Function, Release and Clearance.

Critical reviews in immunology - 1 Jan 2017

Bemelmans M H A, van Tits L J H, Buurman W A

Abstract excerpt

Tumor Necrosis Factor (TNF) is a multifunctional cytokine. It plays an important role in the pathophysiology of several diseases. Recently, it has been discovered that TNF is circulating in two different forms, a bioactive form and an immunologically detectable form. These two forms of TNF show different clearance kinetics. The immunological form is supposed to be an inactivated TNF protein. For this...

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Source

Identifiers

PMID: 29773022
DOI: 10.1615/CritRevImmunol.v37.i2-6.50

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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