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Article

Maternal human telomerase reverse transcriptase variants are associated with preterm labor and preterm premature rupture of membranes.

PloS one - 1 Jan 2018

Marrs Caroline, Chesmore Kevin, Menon Ramkumar, Williams Scott

Abstract excerpt

OBJECTIVE: Premature aging and short telomere lengths of fetal tissues are associated with spontaneous preterm labor (PTL) and preterm premature rupture of membranes (pPROM). Maintenance of telomere length is performed by the enzyme telomerase. Human telomerase reverse transcriptase (hTERT) is a subunit of telomerase, and its dysfunction affects telomere shortening. This study assessed whether maternal or fetal...

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Identifiers

PMID: 29771920
DOI: 10.1371/journal.pone.0195963
PMCID: PMC5957404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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