Article
Mother's and child's methylenetetrahydrofolate reductase C677T polymorphism is associated with preterm delivery and low birth weight.
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Jun 2004
Chen Da-fang, Hu Yong-hua, Yang Fan, Wu Bai-yan, Chen Li, Fang Zhi-an, Wang Li-hua
Abstract excerpt
OBJECTIVE: To investigate the association of the C677T polymorphism of the 5,10-methyleneterahydrofolate reductase(MTHFR) gene with preterm delivery(PTD) and low birth weight (LBW). METHODS: A total of 250 normal gestational age families and 250 PTD families were enrolled in the study. Polymerase Chain Reaction (PCR) followed by restriction enzyme digestion were used for genotyping the polymorphism of MTHFR...
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