Article
The Ancient Phosphatidylinositol 3-Kinase Signaling System Is a Master Regulator of Energy and Carbon Metabolism in Algae.
Plant physiology - 1 Jul 2018
Ramanan Rishiram, Tran Quynh-Giao, Cho Dae-Hyun, Jung Jae-Eun, Kim Byung-Hyuk, Shin Sang-Yoon, Choi Sae-Hae, Liu Kwang-Hyeon, Kim Dae-Soo, Lee Seon-Jin, Crespo José L, Lee Hee-Gu, Oh Hee-Mock, Kim Hee-Sik
Abstract excerpt
Algae undergo a complete metabolic transformation under stress by arresting cell growth, inducing autophagy and hyper-accumulating biofuel precursors such as triacylglycerols and starch. However, the regulatory mechanisms behind this stress-induced transformation are still unclear. Here, we use biochemical, mutational, and "omics" approaches to demonstrate that PI3K signaling mediates the homeostasis of energy...
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