Quantitative analysis of a new marker for common acute lymphoblastic leukemia detected by two-dimensional electrophoresis.

Abstract excerpt

A major subtype of childhood lymphoblastic leukemia has been previously defined on the basis of expression of a cell surface marker referred to as the common acute lymphoblastic leukemia antigen. In this study we provide evidence that leukemic cells from most of the patients with common acute lymphoblastic leukemia contain a cytosolic polypeptide designated L4, the occurrence of which is strongly correlated with...

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