Article
Insight into the mechanisms and consequences of recurrent telomere capture associated with a sub-telomeric deletion.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology - 1 Sept 2018
Dos Santos Alexsandro, Campagnari Francine, Krepischi Ana Cristina Victorino, Ribeiro Câmara Maria de Lourdes, de Arruda Brasil Rita de Cássia E, Vieira Ligia, Vianna-Morgante Angela M, Otto Paulo A, Pearson Peter L, Rosenberg Carla
Abstract excerpt
A complex mosaicism of the short arm of chromosome 1 detected by SNP microarray analysis is described in a patient presenting a 4-Mb 1p36 terminal deletion and associated phenotypic features. The array pattern of chromosome 1p displayed an intriguing increase in divergence of the SNP heterozygote frequency from the expected 50% from the centromere towards the 1p36 breakpoint. This suggests that various...
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