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Article

A tag SNP in syncytin-2 3-UTR significantly correlates with the risk of severe preeclampsia.

Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2018

Hua Ying, Wang Jing, Yuan Dong-Lan, Qi Yaozhi, Tang Zuoqing, Zhu Xueqiong, Jiang Shi-Wen

Abstract excerpt

BACKGROUND: Preeclampsia is a disease that frequently complicates pregnancy and poses a serious threat to maternal and fetal health. The causes and pathogenic mechanisms of preeclampsia are poorly defined. Genetic predisposition could be an important etiological factor. Previous studies have demonstrated that syncytin-1 and syncytin-2, encoded by the genes ERVWE1 and ERVFRDE-1, are involved in the pathogenesis of...

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Identifiers

PMID: 29750965
DOI: 10.1016/j.cca.2018.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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