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Association between SOX9 and CA9 in glioma, and its effects on chemosensitivity to TMZ

26 Apr 2018

Abstract excerpt

Temozolomide (TMZ) is a standard chemotherapeutic drug used in the treatment of glioblastoma multiforme (GBM); however, resistance to this drug is common. SRY-Box 9 (SOX9) expression is associated with a poor prognosis of patients with GBM and with resistance to TMZ. Therefore, the aim of this study was to examine the effects of SOX9 inhibition on the sensitivity of glioma cells to TMZ treatment. We knocked down...

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Identifiers

PMID: 29749469
DOI: 10.3892/ijo.2018.4382

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