Article
XPF polymorphism toward lung cancer susceptibility and survival in patients treated with platinum-based chemotherapy.
Future oncology (London, England) - 1 May 2018
Lawania Shweta, Sharma Siddharth, Singh Navneet, Behera Digamber
Abstract excerpt
AIM: To evaluate the association of three XPF polymorphic variants (673 C>T, 11985 A>G, G415A) with lung cancer, overall survival and clinical response in North Indians. METHODS: Genotyping was performed using PCR-restriction fragment length polymorphism. RESULTS: A total of 673 C>T polymorphism was associated with 1.5-fold increased lung cancer risk for heterozygous genotype (CT; p = 0.03). Adenocarcinoma...
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