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hTERT rs2735940 polymorphism influences lung cancer risk and overall survival in lung cancer patients undergoing platinum-based doublet chemotherapy.

Expert review of molecular diagnostics - 1 Oct 2025

Saini Anjali, Kansal Heena, Singh Navneet, Sharma Siddharth

Abstract excerpt

BACKGROUND: The hTERT gene is an essential part of the telomerase enzyme, preserving telomere length and encouraging cellular immortality. The study aimed to investigate whether the TERT gene SNP was associated with an increased risk of lung cancer in the North Indian population. RESEARCH DESIGN AND METHODS: 387 lung cancer patients undergoing platinum-based chemotherapy and 384 healthy controls were genotyped...

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Identifiers

PMID: 40310442
DOI: 10.1080/14737159.2025.2500657

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TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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