Article
Pathogenic Gene Screening of Mycobacterium tuberculosis by Literature Data Mining and Information Pathway Enrichment Analysis.
Clinical laboratory - 1 May 2018
Xu Guangyu, Wen Simin, Pan Yuchen, Zhang Nan, Wang Yuanyi
Abstract excerpt
BACKGROUND: Recent studies have unraveled mutations which have led to changes in the original conformation of functional proteins targeted by frontline drugs against Mycobacterium tuberculosis. These mutations are likely responsible for the emergence of drug-resistant strains of M. tuberculosis. Identification of new therapeutic targets is fundamental to the development of novel anti-TB drugs. METHODS: Boost...
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