Article
Identification of Novel Acinetobacter baumannii Type VI Secretion System Antibacterial Effector and Immunity Pairs.
Infection and immunity - 1 Aug 2018
Fitzsimons Timothy C, Lewis Jessica M, Wright Amy, Kleifeld Oded, Schittenhelm Ralf B, Powell David, Harper Marina, Boyce John D
Abstract excerpt
The type VI secretion system (T6SS) is a macromolecular machine that delivers protein effectors into host cells and/or competing bacteria. The effectors may be delivered as noncovalently bound cargo of T6SS needle proteins (VgrG/Hcp/PAAR) or as C-terminal extensions of these proteins. Many Acinetobacter baumannii strains produce a T6SS, but little is known about the specific effectors or how they are delivered....
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