Downregulation of aldose reductase is responsible for developmental abnormalities of the silkworm purple quail-like mutant (q-lp).

doi:10.1016/j.gene.2018.05.010

Article

Downregulation of aldose reductase is responsible for developmental abnormalities of the silkworm purple quail-like mutant (q-lp).

Gene - 30 Jul 2018

Wang Pingyang, Bi Simin, Wei Weiyang, Qiu Zhiyong, Xia Dingguo, Shen Xingjia, Zhao Qiaoling

Abstract excerpt

Aldose reductase (AR) is a rate-limiting enzyme in the polyol pathway and is also the key enzyme involved in diabetic complications. The silkworm purple quail-like mutant (q-lp) exhibits pigmented dots on its epidermis. The q-lp mutant also shows developmental abnormalities and decreased vitality. In this study, fat bodies from the q-lp mutant and the wildtype 932VR strain were subjected to two-dimensional gel...

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Downregulation of aldose reductase is responsible for developmental abnormalities of the silkworm purple quail-like mutant (q-lp).

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Downregulation of aldose reductase is responsible for developmental abnormalities of the silkworm purple quail-like mutant (q-lp).

Abstract excerpt

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