Study of GCH1 and TH genes in Chinese patients with Parkinson's disease.

doi:10.1016/j.neurobiolaging.2018.02.004

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Article

Study of GCH1 and TH genes in Chinese patients with Parkinson's disease.

Neurobiology of aging - 1 Aug 2018

Yan Ya-Ping, Zhang Bo, Shen Ting, Si Xiao-Li, Guo Zhang-Yu, Tian Jun, Xu Cong-Ying, Zhang Bao-Rong

Abstract excerpt

Whole-exome sequencing of Parkinson's disease (PD) patients has revealed that the frequency of GTP-cyclohydrolase I (GCH1) variants was signiﬁcantly higher in patients than in controls. GCH1 rs11158026 was also found to increase the risk of PD. To investigate genetic contribution of dopa-responsive dystonia-related genes to PD, GCH1, and tyrosine hydroxylase (TH) were tested in PD patients. A total of 859 study...

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PMID: 29724574
DOI: 10.1016/j.neurobiolaging.2018.02.004

Genes

GCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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